PlumX Metrics
Embed PlumX Metrics

Cellular and subcellular localization of γ -aminobutyric acid B receptors in the rat olfactory bulb

Neuroscience Letters, ISSN: 0304-3940, Vol: 274, Issue: 3, Page: 195-198
1999
  • 40
    Citations
  • 0
    Usage
  • 31
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Article Description

Olfactory nerve axons terminate in rounded regions of the olfactory bulb, termed glomeruli, where they make excitatory synapses with the dendrites of second-order neurons. Neurotransmission from the olfactory nerve to the postsynaptic targets is negatively regulated by γ -aminobutyric acid (GABA), and there is evidence that inhibition of sensory input is mediated, at least in part, by GABA B receptors. Using an antiserum that recognizes two GABA B receptor splice variants (GBR1a and GBR1b), we show here that GABA B receptors are located on the axon terminals of the olfactory nerve, where they are concentrated at sites of axodendritic apposition. Taken with previous data, these results indicate that GABA B receptors act presynaptically to regulate the release of glutamate from olfactory nerve terminals.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know