Cellular and subcellular localization of γ -aminobutyric acid B receptors in the rat olfactory bulb
Neuroscience Letters, ISSN: 0304-3940, Vol: 274, Issue: 3, Page: 195-198
1999
- 40Citations
- 31Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations40
- Citation Indexes40
- 40
- CrossRef32
- Captures31
- Readers31
- 31
Article Description
Olfactory nerve axons terminate in rounded regions of the olfactory bulb, termed glomeruli, where they make excitatory synapses with the dendrites of second-order neurons. Neurotransmission from the olfactory nerve to the postsynaptic targets is negatively regulated by γ -aminobutyric acid (GABA), and there is evidence that inhibition of sensory input is mediated, at least in part, by GABA B receptors. Using an antiserum that recognizes two GABA B receptor splice variants (GBR1a and GBR1b), we show here that GABA B receptors are located on the axon terminals of the olfactory nerve, where they are concentrated at sites of axodendritic apposition. Taken with previous data, these results indicate that GABA B receptors act presynaptically to regulate the release of glutamate from olfactory nerve terminals.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0304394099006977; http://dx.doi.org/10.1016/s0304-3940(99)00697-7; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0032843732&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/10548423; https://linkinghub.elsevier.com/retrieve/pii/S0304394099006977; http://linkinghub.elsevier.com/retrieve/pii/S0304394099006977; http://api.elsevier.com/content/article/PII:S0304394099006977?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S0304394099006977?httpAccept=text/plain; http://dx.doi.org/10.1016/s0304-3940%2899%2900697-7; https://dx.doi.org/10.1016/s0304-3940%2899%2900697-7
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