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Genome instability in a region of human DNA enriched in Alu repeat sequences

Nature, ISSN: 0028-0836, Vol: 296, Issue: 5854, Page: 219-225
1982
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Article Description

DNA rearrangements involving restriction fragment length polymorphism and variation in copy number were detected in the human genome by blot hybridization with a cloned segment of human DNA initially present in a cluster of Alu repeat sequences. These rearrangements involve both extrachromosomal circular duplex DNAs and integrated sequences, indicating the presence of transposable elements in human cells. © 1982 Nature Publishing Group.

Bibliographic Details

Bruno Calabretta; Hugo A. Barrera-saldana; Grady F. Saunders; Donald L. Robberson; Thymios P. Lambrou

Springer Science and Business Media LLC

Multidisciplinary

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